Skip Navigation
Skip to contents

ACC : Acute and Critical Care

OPEN ACCESS
SEARCH
Search

Previous issues

Page Path
HOME > Issue > Previous issues
9 Previous issues
Filter
Filter
Article category
Keywords
Authors
Funded articles
Volume 33 (2); May 2018
Prev issue Next issue
Review
Basic science and research
Role of Mitochondrial Oxidative Stress in Sepsis
Harsha Nagar, Shuyu Piao, Cuk-Seong Kim
Acute Crit Care. 2018;33(2):65-72.   Published online May 31, 2018
DOI: https://doi.org/10.4266/acc.2018.00157
  • 7,361 View
  • 388 Download
  • 43 Citations
AbstractAbstract PDF
Mitochondria are considered the power house of the cell and are an essential part of the cellular infrastructure, serving as the primary site for adenosine triphosphate production via oxidative phosphorylation. These organelles also release reactive oxygen species (ROS), which are normal byproducts of metabolism at physiological levels; however, overproduction of ROS under pathophysiological conditions is considered part of a disease process, as in sepsis. The inflammatory response inherent in sepsis initiates changes in normal mitochondrial functions that may result in organ damage. There is a complex system of interacting antioxidant defenses that normally function to combat oxidative stress and prevent damage to the mitochondria. It is widely accepted that oxidative stress-mediated injury plays an important role in the development of organ failure; however, conclusive evidence of any beneficial effect of systemic antioxidant supplementation in patients with sepsis and organ dysfunction is lacking. Nevertheless, it has been suggested that antioxidant therapy delivered specifically to the mitochondria may be useful.

Citations

Citations to this article as recorded by  
  • Macrophages-regulating nanomedicines for sepsis therapy
    Jiali Deng, Rui Wang, Shu Huang, Jinsong Ding, Wenhu Zhou
    Chinese Chemical Letters.2023; 34(3): 107588.     CrossRef
  • A pilot study on the melatonin treatment in patients with early septic shock: results of a single-center randomized controlled trial
    Abbas Taher, Farnaz Shokoohmand, Elham Abdoli, Younes Mohammadi, Maryam Mehrpooya
    Irish Journal of Medical Science (1971 -).2022; 191(4): 1913.     CrossRef
  • Biomarker Analysis for Combination Therapy of Vitamin C and Thiamine in Septic Shock: A Post-Hoc Study of the ATESS Trial
    Jong Eun Park, You Hwan Jo, Sung Yeon Hwang, Won Young Kim, Seung Mok Ryoo, Dong-Hyun Jang, Taegyun Kim, Youn-Jung Kim, Seonwoo Kim, Hyun Cho, Gun Tak Lee, Sung Phil Chung, Sung-Hyuk Choi, Tae Gun Shin, Gil Joon Suh
    Shock.2022; 57(1): 81.     CrossRef
  • Anagliptin prevents lipopolysaccharide (LPS)- induced inflammation and activation of macrophages
    Fangfang Yu, Wenxia Tian, Jie Dong
    International Immunopharmacology.2022; 104: 108514.     CrossRef
  • Pink1/Parkin-Mediated Mitophagy Regulated the Apoptosis of Dendritic Cells in Sepsis
    Yaolu Zhang, Longwang Chen, Yinan Luo, Kang Wang, Xinyong Liu, Zhong Xiao, Guangju Zhao, Yongming Yao, Zhongqiu Lu
    Inflammation.2022; 45(3): 1374.     CrossRef
  • Inhibition of mitoNEET attenuates LPS-induced inflammation and oxidative stress
    Seunghee Lee, Byeong Geun Seok, Seon-Jin Lee, Su Wol Chung
    Cell Death & Disease.2022;[Epub]     CrossRef
  • An update in the utilization of N-acetyl cysteine & vitamin c for tackling the oxidative stress in acute kidney injury secondary to robust sepsis - A systematic review
    Kaur Kulvinder Kochar, Allahbadia Gautam , Singh Mandeep
    Journal of Clinical Nephrology.2022; 6(1): 001.     CrossRef
  • Mitochondrial Protein Akap1 Deletion Exacerbates Endoplasmic Reticulum Stress in Mice Exposed to Hyperoxia
    Sahebgowda Sidramagowda Patil, Ramani Soundararajan, Jutaro Fukumoto, Mason Breitzig, Helena Hernández-Cuervo, Matthew Alleyn, Muling Lin, Venkata Ramireddy Narala, Richard Lockey, Narasaiah Kolliputi, Lakshmi Galam
    Frontiers in Pharmacology.2022;[Epub]     CrossRef
  • COVID-19, Oxidative Stress, and Neuroinflammation in the Depression Route
    Maiqueli Eduarda Dama Mingoti, Amanda Gollo Bertollo, Júlia Leão Batista Simões, Gabriel Rossi Francisco, Margarete Dulce Bagatini, Zuleide Maria Ignácio
    Journal of Molecular Neuroscience.2022; 72(6): 1166.     CrossRef
  • Low-power infrared laser modulates mRNA levels from genes of base excision repair and genomic stabilization in heart tissue from an experimental model of acute lung injury
    Larissa Alexsandra da Silva Neto Trajano, Luiz Philippe da Silva Sergio, Diego Sá Leal de Oliveira, Eduardo Tavares Lima Trajano, Marco Aurélio dos Santos Silva, Flávia de Paoli, André Luiz Mencalha, Adenilson de Souza da Fonseca
    Photochemical & Photobiological Sciences.2022; 21(7): 1299.     CrossRef
  • Landscape of Metabolic Fingerprinting for Diagnosis and Risk Stratification of Sepsis
    Geng Lu, Jiawei Zhou, Ting Yang, Jin Li, Xinrui Jiang, Wenjun Zhang, Shuangshuang Gu, Jun Wang
    Frontiers in Immunology.2022;[Epub]     CrossRef
  • Nano-curcumin supplementation in critically ill patients with sepsis: a randomized clinical trial investigating the inflammatory biomarkers, oxidative stress indices, endothelial function, clinical outcomes and nutritional status
    Arash Karimi, Fatemeh Naeini, Hamid Reza Niazkar, Helda Tutunchi, Vali Musazadeh, Ata Mahmoodpoor, Vahid Asghariazar, Majid Mobasseri, Ali Tarighat-Esfanjani
    Food & Function.2022; 13(12): 6596.     CrossRef
  • An Overview on Mitochondrial-Based Therapies in Sepsis-Related Myocardial Dysfunction: Mitochondrial Transplantation as a Promising Approach
    Behnaz Mokhtari, Rana Yavari, Reza Badalzadeh, Ata Mahmoodpoor, Jayaraman Tharmalingam
    Canadian Journal of Infectious Diseases and Medical Microbiology.2022; 2022: 1.     CrossRef
  • p66Shc in Cardiovascular Pathology
    Landon Haslem, Jennifer M. Hays, Franklin A. Hays
    Cells.2022; 11(11): 1855.     CrossRef
  • Ablation of long noncoding RNA MALAT1 activates antioxidant pathway and alleviates sepsis in mice
    Jingshu Chen, Shu Tang, Sui Ke, James J. Cai, Daniel Osorio, Andrei Golovko, Benjamin Morpurgo, Shaodong Guo, Yuxiang Sun, Melanie Winkle, George A. Calin, Yanan Tian
    Redox Biology.2022; 54: 102377.     CrossRef
  • Comparison enteral superoxide dismutase 1 IU and 5 IU from Cucumis melo L.C extract combined with gliadin as an antioxidant and anti-inflammatory in LPS-Induced sepsis model rats
    Cut Meliza Zainumi, Gontar Alamsyah Siregar, Dadik Wahyu Wijaya, Muhammad Ichwan
    Heliyon.2022; 8(8): e10236.     CrossRef
  • Evidence-based updates to the 2021 Surviving Sepsis Campaign guidelines
    Karen D. Lehman
    The Nurse Practitioner.2022; 47(11): 24.     CrossRef
  • Stimuli-responsive and biomimetic delivery systems for sepsis and related complications
    Eman A. Ismail, Nikita Devnarain, Thirumala Govender, Calvin A. Omolo
    Journal of Controlled Release.2022; 352: 1048.     CrossRef
  • P66Shc (Shc1) Zebrafish Mutant Line as a Platform for Testing Decreased Reactive Oxygen Species in Pathology
    Landon Haslem, Jennifer M. Hays, Xin A. Zhang, Franklin A. Hays
    Journal of Cardiovascular Development and Disease.2022; 9(11): 385.     CrossRef
  • Low dimensional nanomaterials for treating acute kidney injury
    Yuanpeng Nie, Liying Wang, Xinru You, Xiaohua Wang, Jun Wu, Zhihua Zheng
    Journal of Nanobiotechnology.2022;[Epub]     CrossRef
  • Hydroxytyrosol ameliorates oxidative challenge and inflammatory response associated with lipopolysaccharide-mediated sepsis in mice
    Mohamed A Alblihed
    Human & Experimental Toxicology.2021; 40(2): 342.     CrossRef
  • Advances in sepsis diagnosis and management: a paradigm shift towards nanotechnology
    Amit Pant, Irene Mackraj, Thirumala Govender
    Journal of Biomedical Science.2021;[Epub]     CrossRef
  • Targeting the TXNIP‐NLRP3 interaction with PSSM1443 to suppress inflammation in sepsis‐induced myocardial dysfunction
    Linhua Wang, Hongsheng Zhao, Huifen Xu, Xiangxin Liu, Xinlong Chen, Qingyun Peng, Mingbing Xiao
    Journal of Cellular Physiology.2021; 236(6): 4625.     CrossRef
  • Mitochondrial gene mutations in pediatric septic shock
    Junsung Park, Eunju Kang, Seoon Kang, Deokhoon Kim, Dahyun Kim, Seong Jong Park, Won Kyoung Jhang
    Pediatric Research.2021; 90(5): 1016.     CrossRef
  • Polymeric Antioxidant Materials for Treatment of Inflammatory Disorders
    Jiwon Yeo, Junseok Lee, Sanggi Lee, Won Jong Kim
    Advanced Therapeutics.2021; 4(4): 2000270.     CrossRef
  • Pathophysiology of sepsis
    Pietro Arina, Mervyn Singer
    Current Opinion in Anaesthesiology.2021; 34(2): 77.     CrossRef
  • Oxidative Stress and Endothelial Dysfunction in Sepsis and Acute Inflammation
    Jérémie Joffre, Judith Hellman
    Antioxidants & Redox Signaling.2021; 35(15): 1291.     CrossRef
  • The Prospects of Succinates’ Use under Hypoxic Conditions in COVID-19
    Yu. Р. Orlov, V. V. Afanasyev, I. A. Khilenko
    Antibiotics and Chemotherapy.2021; 66(1-2): 65.     CrossRef
  • On the Possibility of Using Succinate in Hypoxia Developing in COVID-19
    Yu. P. Orlov, N. V. Govorova, O. V. Korpacheva, V. V. Afanasyev, I. A. Khilenko
    General Reanimatology.2021; 17(3): 78.     CrossRef
  • Sepsis: Evidence-based pathogenesis and treatment
    Jay Pravda
    World Journal of Critical Care Medicine.2021; 10(4): 66.     CrossRef
  • Albumin Oxidation Status in Sepsis Patients Treated With Albumin or Crystalloids
    Matteo Bonifazi, Jennifer Meessen, Alba Pérez, Francesco Vasques, Mattia Busana, Francesco Vassalli, Deborah Novelli, Roberto Bernasconi, Chiara Signori, Serge Masson, Federica Romitti, Lorenzo Giosa, Matteo Macrì, Iacopo Pasticci, Maria Michela Palumbo,
    Frontiers in Physiology.2021;[Epub]     CrossRef
  • Preliminary Findings on the Association of the Lipid Peroxidation Product 4-Hydroxynonenal with the Lethal Outcome of Aggressive COVID-19
    Neven Žarković, Biserka Orehovec, Lidija Milković, Bruno Baršić, Franz Tatzber, Willibald Wonisch, Marko Tarle, Marta Kmet, Ana Mataić, Antonia Jakovčević, Tea Vuković, Danijela Talić, Georg Waeg, Ivica Lukšić, Elzbieta Skrzydlewska, Kamelija Žarković
    Antioxidants.2021; 10(9): 1341.     CrossRef
  • Targeting Oxidative Stress in Septic Acute Kidney Injury: From Theory to Practice
    Connie P. C. Ow, Anton Trask-Marino, Ashenafi H. Betrie, Roger G. Evans, Clive N. May, Yugeesh R. Lankadeva
    Journal of Clinical Medicine.2021; 10(17): 3798.     CrossRef
  • The Effects of a Meldonium Pre-Treatment on the Course of the Faecal-Induced Sepsis in Rats
    Siniša Đurašević, Aleksandra Ružičić, Iva Lakić, Tomislav Tosti, Saša Đurović, Sofija Glumac, Slađan Pavlović, Slavica Borković-Mitić, Ilijana Grigorov, Sanja Stanković, Nebojša Jasnić, Jelena Đorđević, Zoran Todorović
    International Journal of Molecular Sciences.2021; 22(18): 9698.     CrossRef
  • TRP Channels as Sensors of Aldehyde and Oxidative Stress
    Katharina E. M. Hellenthal, Laura Brabenec, Eric R. Gross, Nana-Maria Wagner
    Biomolecules.2021; 11(10): 1401.     CrossRef
  • Intramuscular Exposure to a Lethal Dose of Ricin Toxin Leads to Endothelial Glycocalyx Shedding and Microvascular Flow Abnormality in Mice and Swine
    Anita Sapoznikov, Yoav Gal, Yentl Evgy, Moshe Aftalion, Shahaf Katalan, Tamar Sabo, Chanoch Kronman, Reut Falach
    International Journal of Molecular Sciences.2021; 22(22): 12345.     CrossRef
  • LBP Protects Hepatocyte Mitochondrial Function Via the PPAR-CYP4A2 Signaling Pathway in a Rat Sepsis Model
    Zichen Song, Leilei Meng, Zhixiang He, Jing Huang, Fang Li, Jingjing Feng, Zhuoran Jia, Yue Huang, Wei Liu, Anding Liu, Haoshu Fang
    Shock.2021; 56(6): 1066.     CrossRef
  • Common Inflammatory Mechanisms in COVID-19 and Parkinson’s Diseases: The Role of Microbiome, Pharmabiotics and Postbiotics in Their Prevention
    Valery Danilenko, Andrey Devyatkin, Mariya Marsova, Madina Shibilova, Rustem Ilyasov, Vladimir Shmyrev
    Journal of Inflammation Research.2021; Volume 14: 6349.     CrossRef
  • Immunomodulatory Effect of Doxycycline Ameliorates Systemic and Pulmonary Inflammation in a Murine Polymicrobial Sepsis Model
    Anasuya Patel, Hemant Khande, Hariharan Periasamy, Santosh Mokale
    Inflammation.2020; 43(3): 1035.     CrossRef
  • Agaricus brasiliensis Mushroom Protects Against Sepsis by Alleviating Oxidative and Inflammatory Response
    Kely Campos Navegantes-Lima, Valter Vinicius Silva Monteiro, Silvia Leticia de França Gaspar, Ana Ligia de Brito Oliveira, Juliana Pinheiro de Oliveira, Jordano Ferreira Reis, Rafaelli de Souza Gomes, Caroline Azulay Rodrigues, Herta Stutz, Vanessa Sovran
    Frontiers in Immunology.2020;[Epub]     CrossRef
  • Oxidative Stress and Inflammation in COVID-19-Associated Sepsis: The Potential Role of Anti-Oxidant Therapy in Avoiding Disease Progression
    Jesús Beltrán-García, Rebeca Osca-Verdegal, Federico V. Pallardó, José Ferreres, María Rodríguez, Sandra Mulet, Fabian Sanchis-Gomar, Nieves Carbonell, José Luis García-Giménez
    Antioxidants.2020; 9(10): 936.     CrossRef
  • Molecular mechanisms of organ damage in sepsis: an overview
    Grażyna Sygitowicz, Dariusz Sitkiewicz
    The Brazilian Journal of Infectious Diseases.2020; 24(6): 552.     CrossRef
  • Azithromycin in Combination with Ceftriaxone Reduces Systemic Inflammation and Provides Survival Benefit in a Murine Model of Polymicrobial Sepsis
    Anasuya Patel, Jiji Joseph, Hariharan Periasamy, Santosh Mokale
    Antimicrobial Agents and Chemotherapy.2018;[Epub]     CrossRef
Original Articles
Infection
Current Status and Survival Impact of Infectious Disease Consultation for Multidrug-Resistant Bacteremia in Ventilated Patients: A Single-Center Experience in Korea
Insu Kim, Won-Young Kim, Eun Suk Jeoung, Kwangha Lee
Acute Crit Care. 2018;33(2):73-82.   Published online April 26, 2018
DOI: https://doi.org/10.4266/acc.2017.00591
  • 4,780 View
  • 105 Download
  • 3 Citations
AbstractAbstract PDF
Background
We evaluated the current status and survival impact of infectious disease consultation (IDC) in ventilated patients with multidrug-resistant (MDR) bacteremia.
Methods
One hundred sixty-one consecutive patients from a single tertiary care hospital were enrolled over a 5-year period. Patients with at least one of the following six MDR bacteremias were included: methicillin-resistant Staphylococcus aureus, extended-spectrum β-lactamase-producing gram-negative bacteria (Escherichia coli and Klebsiella pneumonia), carbapenem-resistant gram-negative rods (Acinetobacter baumannii and Pseudomonas aeruginosa), and vancomycin-resistant Enterococcus faecium.
Results
Median patient age was 66 years (range, 18 to 95), and 57.8% of subjects were male. The 28-day mortality after the day of blood culture was 52.2%. An IDC was requested for 96 patients based on a positive blood culture (59.6%). Patients without IDC had significantly higher rate of hemato-oncologic diseases as a comorbidity (36.9% vs. 11.5%, P < 0.001). Patients without an IDC had higher Acute Physiology and Chronic Health Evaluation (APACHE) II score (median, 20; range, 8 to 38 vs. median, 16; range, 5 to 34, P < 0.001) and Sequential Organ Failure Assessment (SOFA) score (median, 9; range, 2 to 17 vs. median, 7; range, 2 to 20; P = 0.020) on the day of blood culture and a higher 28-day mortality rate (72.3% vs. 38.5%, P < 0.001). In patients with SOFA ≥9 (cut-off level based on Youden’s index) on the day of blood culture and gram-negative bacteremia, IDC was also significantly associated with lower 28-day mortality (hazard ratio [HR], 0.298; 95% confidence interval [CI], 0.167 to 0.532 and HR, 0.180; 95% CI, 0.097 to 0.333; all P < 0.001] based on multivariate Cox regression analysis.
Conclusions
An IDC for MDR bacteremia was requested less often for ventilated patients with greater disease severity and higher 28- day mortality after blood was drawn. In patients with SOFA ≥9 on the day of blood culture and gram-negative bacteremia, IDC was associated with improved 28-day survival after blood draw for culture.

Citations

Citations to this article as recorded by  
  • Impact of infectious diseases consultation among patients with infections caused by gram-negative rod bacteria: a systematic literature review and meta-analysis
    Shinya Hasegawa, Satoshi Kakiuchi, Joseph Tholany, Takaaki Kobayashi, Alexandre R. Marra, Marin L. Schweizer, Riley J. Samuelson, Hiroyuki Suzuki
    Infectious Diseases.2022; 54(8): 618.     CrossRef
  • Infectious Disease Consults of Pseudomonas aeruginosa Bloodstream Infection and Impact on Health Outcomes
    Swetha Ramanathan, Fritzie S Albarillo, Margaret A Fitzpatrick, Katie J Suda, Linda Poggensee, Amanda Vivo, Martin E Evans, Makoto Jones, Nasia Safdar, Chris Pfeiffer, Bridget Smith, Geneva Wilson, Charlesnika T Evans
    Open Forum Infectious Diseases.2022;[Epub]     CrossRef
  • Timeliness of Infectious Diseases Referral and Inappropriate Antibiotic Usage Post-Referral in an Asian Tertiary Hospital
    Liang En Wee, Aidan Lyanzhiang Tan, Limin Wijaya, Maciej Piotr Chlebicki, Julian Thumboo, Ban Hock Tan
    Tropical Medicine and Infectious Disease.2019; 4(4): 137.     CrossRef
CPR/Resuscitation
APACHE II Score Immediately after Cardiac Arrest as a Predictor of Good Neurological Outcome in Out-of-Hospital Cardiac Arrest Patients Receiving Targeted Temperature Management
Sang-Il Kim, Youn-Jung Kim, You-Jin Lee, Seung Mok Ryoo, Chang Hwan Sohn, Dong Woo Seo, Yoon-Seon Lee, Jae Ho Lee, Kyoung Soo Lim, Won Young Kim
Acute Crit Care. 2018;33(2):83-88.   Published online May 31, 2018
DOI: https://doi.org/10.4266/acc.2017.00514
  • 4,851 View
  • 92 Download
  • 3 Citations
AbstractAbstract PDF
Background
This study assessed the association between the initial Acute Physiology and Chronic Health Evaluation (APACHE) II score and good neurological outcome in comatose survivors of out-of-hospital cardiac arrest who received targeted temperature management (TTM).
Methods
Data from survivors of cardiac arrest who received TTM between January 2011 and June 2016 were retrospectively analyzed. The initial APACHE II score was determined using the data immediately collected after return of spontaneous circulation rather than within 24 hours after being admitted to the intensive care unit. Good neurological outcome, defined as Cerebral Performance Category 1 or 2 on day 28, was the primary outcome of this study.
Results
Among 143 survivors of cardiac arrest who received TTM, 62 (43.4%) survived, and 34 (23.8%) exhibited good neurological outcome on day 28. The initial APACHE II score was significantly lower in the patients with good neurological outcome than in those with poor neurological outcome (23.71 ± 4.39 vs. 27.62 ± 6.16, P = 0.001). The predictive ability of the initial APACHE II score for good neurological outcome, assessed using the area under the receiver operating characteristic curve, was 0.697 (95% confidence interval [CI], 0.599 to 0.795; P = 0.001). The initial APACHE II score was associated with good neurological outcome after adjusting for confounders (odds ratio, 0.878; 95% CI, 0.792 to 0.974; P = 0.014).
Conclusions
In the present study, the APACHE II score calculated in the immediate post-cardiac arrest period was associated with good neurological outcome. The initial APACHE II score might be useful for early identification of good neurological outcome.

Citations

Citations to this article as recorded by  
  • Predicting the survivals and favorable neurologic outcomes after targeted temperature management by artificial neural networks
    Wei-Ting Chiu, Chen-Chih Chung, Chien-Hua Huang, Yu-san Chien, Chih-Hsin Hsu, Cheng-Hsueh Wu, Chen-Hsu Wang, Hung-Wen Chiu, Lung Chan
    Journal of the Formosan Medical Association.2022; 121(2): 490.     CrossRef
  • Artificial neural network-boosted Cardiac Arrest Survival Post-Resuscitation In-hospital (CASPRI) score accurately predicts outcome in cardiac arrest patients treated with targeted temperature management
    Szu-Yi Chou, Oluwaseun Adebayo Bamodu, Wei-Ting Chiu, Chien-Tai Hong, Lung Chan, Chen-Chih Chung
    Scientific Reports.2022;[Epub]     CrossRef
  • Novel Approaches to Risk Stratification of In-Hospital Cardiac Arrest
    Jason J. Yang, Xiao Hu, Noel G. Boyle, Duc H. Do
    Current Cardiovascular Risk Reports.2021;[Epub]     CrossRef
Surgery
Feasibility of Percutaneous Dilatational Tracheostomy with a Light Source in the Surgical Intensive Care Unit
Jong-Kwan Baek, Jung-Sun Lee, Minchang Kang, Nak-Jun Choi, Suk-Kyung Hong
Acute Crit Care. 2018;33(2):89-94.   Published online April 26, 2018
DOI: https://doi.org/10.4266/acc.2017.00563
  • 4,245 View
  • 107 Download
  • 2 Citations
AbstractAbstract PDF
Background
Although percutaneous dilatational tracheostomy (PDT) under bronchoscopic guidance is feasible in the intensive care unit (ICU), it requires extensive equipment and specialists. The present study evaluated the feasibility of performing PDT with a light source in the surgical ICU.
Methods
The study involved a retrospective review of the outcomes of patients who underwent PDT with a light source performed by a surgery resident under the supervision of a surgical intensivist in the surgical ICU from October 2015 through September 2016. During the procedure, a light wand was inserted into the endotracheal tube after skin incision. Then, the light wand and the endotracheal tube were pulled out slightly, the passage of light through the airway was confirmed, and the relevant point was punctured.
Results
Fifty patients underwent PDT with a light source. The average procedural duration was 14.0 ± 7.0 minutes. There were no procedure-associated deaths. Intraoperative complications included minor bleeding in three patients (6%) and paratracheal placement of the tracheostomy tube in one patient (2%); these were immediately resolved by the surgical intensivist. Two patients required conversion to surgical tracheostomy because of the difficulty in light wand insertion into the endotracheal tube and a very narrow trachea, respectively.
Conclusions
PDT with a light source can be performed without bronchoscopy and does not require expensive equipment and specialist intervention in the surgical ICU. It can be safely performed by a surgical intensivist with experience in surgical tracheostomy.

Citations

Citations to this article as recorded by  
  • The feasibility and safety of percutaneous dilatational tracheostomy without endotracheal guidance in the intensive care unit
    Ji Eun Kim, Dong Hyun Lee
    Acute and Critical Care.2022; 37(1): 101.     CrossRef
  • Safety and feasibility of hybrid tracheostomy
    Daeun Kang, In Beom Jeong, Sun Jung Kwon, Ji Woong Son, Gwan Woo Ku
    Acute and Critical Care.2021; 36(4): 369.     CrossRef
Ethics
Transcultural Adaptation and Validation of Quality of Dying and Death Questionnaire in Medical Intensive Care Units in South Korea
Jun Yeun Cho, Jinwoo Lee, Sang-Min Lee, Ju-Hee Park, Junghyun Kim, Youlim Kim, Sang Hoon Lee, Jong Sun Park, Young-Jae Cho, Ho Il Yoon, Jae Ho Lee, Choon-Taek Lee, Yeon Joo Lee
Acute Crit Care. 2018;33(2):95-101.   Published online May 31, 2018
DOI: https://doi.org/10.4266/acc.2017.00612
  • 6,203 View
  • 143 Download
  • 8 Citations
AbstractAbstract PDFSupplementary Material
Background
Providing palliative care to dying patients in the intensive care unit (ICU) has recently received much attention. Evaluating the quality of dying and death (QODD) is important for appropriate comfort care in the ICU. This study aimed to validate the Korean version of the QODD questionnaire.
Methods
This study included decedents in the ICUs of three tertiary teaching hospitals and one secondary hospital from June 2016 to May 2017. ICU staff members were asked to complete the translated QODD questionnaire and the visual analogue scale (VAS) questionnaire within 48 hours of patient death. The validation process consisted of evaluating construct validity, internal consistency, and interrater reliability.
Results
We obtained 416 completed questionnaires describing 255 decedents. The QODD score was positively correlated with the 100-VAS score (Pearson correlation coefficient, 0.348; P<0.001). An evaluation of the internal consistency presented favorable results (calculated Cronbach’s alpha if a given item exceeded 0.8 in all items). The interrater reliability revealed no concordance between doctors and nurses.
Conclusions
The QODD questionnaire was successfully translated and validated in Korean medical ICUs. We hope further studies that use this valuable instrument will be conducted in Korea.

Citations

Citations to this article as recorded by  
  • Change in perception of the quality of death in the intensive care unit by healthcare workers associated with the implementation of the “well-dying law”
    Ye Jin Lee, Soyeon Ahn, Jun Yeun Cho, Tae Yun Park, Seo Young Yun, Junghyun Kim, Jee-Min Kim, Jinwoo Lee, Sang-Min Lee, Jong Sun Park, Young-Jae Cho, Ho Il Yoon, Jae Ho Lee, Choon-Taek Lee, Yeon Joo Lee
    Intensive Care Medicine.2022; 48(3): 281.     CrossRef
  • A systematic review of instruments measuring the quality of dying and death in Asian countries
    Shuo Xu, Yue Fang, Hanzhang Chen, Kang Sun, Chen Zhang, Yang Liu
    Quality of Life Research.2022;[Epub]     CrossRef
  • Translation, Validity and Internal Consistency of the Quality of Dying and Death Questionnaire for Brazilian families of patients that died from cancer: a cross-sectional and methodological study
    Bianca Sakamoto Ribeiro Paiva, Talita Caroline de Oliveira Valentino, Mirella Mingardi, Marco Antonio de Oliveira, Julia Onishi Franco, Michelle Couto Salerno, Helena Palocci, Tais Cruz de Melo, Carlos Eduardo Paiva
    Sao Paulo Medical Journal.2022;[Epub]     CrossRef
  • Factors Associated with Quality of Dying and Death in Korean Intensive Care Units: Perceptions of Nurses
    Haeyoung Lee, Seung-Hye Choi
    Healthcare.2021; 9(1): 40.     CrossRef
  • Validation of the Chinese Version of the Quality of Dying and Death Questionnaire for Family Members of ICU Patients
    Xing-ping Han, Xu Mei, Jing Zhang, Ting-ting Zhang, Ai-ni Yin, Fang Qiu, Meng-jie Liu
    Journal of Pain and Symptom Management.2021; 62(3): 599.     CrossRef
  • Validation of the Quality of Dying and Death Questionnaire among the Chinese populations
    Ying Wang, Mandong Liu, Wallace Chi Ho Chan, Jing Zhou, Iris Chi
    Palliative and Supportive Care.2021; 19(6): 694.     CrossRef
  • The quality of dying and death for patients in intensive care units: a single center pilot study
    Yanghwan Choi, Myoungrin Park, Da Hyun Kang, Jooseon Lee, Jae Young Moon, Heejoon Ahn
    Acute and Critical Care.2019; 34(3): 192.     CrossRef
  • Factors Associated With Quality of Death in Korean ICUs As Perceived by Medical Staff
    Jun Yeun Cho, Ju-Hee Park, Junghyun Kim, Jinwoo Lee, Jong Sun Park, Young-Jae Cho, Ho Il Yoon, Sang-Min Lee, Jae-Ho Lee, Choon-Taek Lee, Yeon Joo Lee
    Critical Care Medicine.2019; 47(9): 1208.     CrossRef
Editorial
Basic science and research
Scoring Systems for the Patients of Intensive Care Unit
Seongwook Jeong
Acute Crit Care. 2018;33(2):102-104.   Published online May 31, 2018
DOI: https://doi.org/10.4266/acc.2018.00185
  • 6,736 View
  • 1,683 Download
  • 10 Citations
PDF

Citations

Citations to this article as recorded by  
  • Diagnostic accuracy of clinical outcome prediction using nursing data in intensive care patients: A systematic review
    Mihui Kim, Sangwoo Park, Changhwan Kim, Mona Choi
    International Journal of Nursing Studies.2023; 138: 104411.     CrossRef
  • Comparison of Pediatric Sequential Organ Failure Assessment and Pediatric Risk of Mortality III Score as Mortality Prediction in Pediatric Intensive Care Unit
    Sadam H Baloch, Ikramullah Shaikh, Murtaza A Gowa, Pooja D Lohano, Mohsina N Ibrahim
    Cureus.2022;[Epub]     CrossRef
  • The efficiency of HALP score, neutrophil-lymphocyte ratio, and platelet-lymphocyte ratio in predicting mortality in intensive care patients
    Salih KOCAOĞLU, Tufan ALATLI
    Journal of Health Sciences and Medicine.2022; 5(1): 201.     CrossRef
  • The Pharmacokinetics of Levetiracetam in Critically Ill Adult Patients: An Intensive Care Unit Clinical Study
    Sophia-Liberty Markantonis, Nikolaos Markou, Apostolos Karagkounis, Dionysia Koutrafouri, Helen Stefanatou, Rania Kousovista, Vangelis Karalis
    Applied Sciences.2022; 12(3): 1208.     CrossRef
  • Usefulness of the d-dimer to albumin ratio for risk assessment in patients with acute variceal bleeding at the emergency department: retrospective observational study
    Jun Seok Seo, Yongwon Kim, Yoonsuk Lee, Ho Young Chung, Tae Youn Kim
    BMC Emergency Medicine.2022;[Epub]     CrossRef
  • The Added Value of Serum Random Cortisol and Thyroid Function Tests as Mortality Predictors for Critically Ill Patients: A Prospective Cohort Study
    Narakorn Muentabutr, Worapaka Manosroi, Nutchanok Niyatiwatchanchai
    Journal of Clinical Medicine.2022; 11(19): 5929.     CrossRef
  • Comparison of mNUTRIC-S2 and mNUTRIC scores to assess nutritional risk and predict intensive care unit mortality
    So Jeong Kim, Hong Yeul Lee, Sun Mi Choi, Sang-Min Lee, Jinwoo Lee
    Acute and Critical Care.2022; 37(4): 618.     CrossRef
  • Perioperative Risk Stratification: A Need for an Improved Assessment in Surgery and Anesthesia—A Pilot Study
    Bianca-Liana Grigorescu, Irina Săplăcan, Marius Petrișor, Ioana Roxana Bordea, Raluca Fodor, Alexandra Lazăr
    Medicina.2021; 57(10): 1132.     CrossRef
  • Intensive Care Unit Mortality Prediction: An Improved Patient-Specific Stacking Ensemble Model
    Nora El-Rashidy, Shaker El-Sappagh, Tamer Abuhmed, Samir Abdelrazek, Hazem M. El-Bakry
    IEEE Access.2020; 8: 133541.     CrossRef
  • Utilizing heart rate variability to predict ICU patient outcome in traumatic brain injury
    Ping Zhang, Tegan Roberts, Brent Richards, Luke J. Haseler
    BMC Bioinformatics.2020;[Epub]     CrossRef
Case Reports
Thoracic Surgery
Chemical Pleurodesis Using Viscum album Extract in Gorham’s Disease Complicated with Chylothorax
Suk Ju Cho, Su Wan Kim
Acute Crit Care. 2018;33(2):105-109.   Published online December 30, 2016
DOI: https://doi.org/10.4266/acc.2016.00164
  • 11,112 View
  • 112 Download
  • 1 Citations
AbstractAbstract PDF
Gorham’s disease, also known as massive osteolysis, is characterized by unregulated proliferation of lymphatic or vascular capillaries within bone, resulting in destruction and replacement with angiomatous tissue. This disease can lead to chylothorax that can be lethal. Viscum album extract from European mistletoe is a complementary anti-cancer drug which is commonly prescribed in many European countries and is considered as a new generation of chemical agent for pleurodesis. A 14-year-old girl presented with dyspnea and chest pain. She was diagnosed as Gorham’s disease who was definitively treated with Viscum album extract for chylothorax that was refractory to standard conservative management.

Citations

Citations to this article as recorded by  
  • Systematic analysis of mistletoe prescriptions in clinical studies
    Henrike Staupe, Judith Buentzel, Christian Keinki, Jens Buentzel, Jutta Huebner
    Journal of Cancer Research and Clinical Oncology.2022;[Epub]     CrossRef
Basic science and research
Anterograde Amnesia after Acute Glufosinate Ammonium Intoxication
Hyuk-Hoon Kim, Young-Gi Min
Acute Crit Care. 2018;33(2):110-113.   Published online May 31, 2018
DOI: https://doi.org/10.4266/acc.2016.00444
  • 5,301 View
  • 122 Download
  • 1 Citations
AbstractAbstract PDF
Glufosinate ammonium (GA) intoxication causes several neurologic complications. We report a rare but typical case of GA intoxication associated with anterograde amnesia and bilateral hippocampal involvement. A 53-year-old woman with GA intoxication presented to the emergency department. Initial general and neurologic examinations were unremarkable but, from the day after admission, she exhibited anterograde amnesia. On brain magnetic resonance imaging, the signal intensity in the hippocampus was symmetrically and bilaterally increased. She was discharged with no medical problems, but the anterograde amnesia remained. Eleven days after the onset of amnesia, she returned to the neurology outpatient department with persisting anterograde amnesia but improving symptoms.

Citations

Citations to this article as recorded by  
  • Prolonged cognitive dysfunction in patient with splenial lesion of the corpus callosum caused by glufosinate ammonium poisoning
    HyunJung Lee, JeongHo Kang
    Turkish Journal of Emergency Medicine.2021; 21(2): 82.     CrossRef
Image in Critical Care
Trauma
Trauma-Induced Retroperitoneal Paraganglioma Rupture Which Was Misunderstood as a Massive Retroperitoneal Hemorrhage
Hongjin Shim, Ji Young Jang, Yeong Ju Kim, Jung Soo Lim, Keum Seok Bae
Acute Crit Care. 2018;33(2):114-116.   Published online April 26, 2018
DOI: https://doi.org/10.4266/acc.2017.00234
  • 4,323 View
  • 88 Download
  • 2 Citations
PDF

Citations

Citations to this article as recorded by  
  • Acute haemoperitoneum caused by ruptured extra‐adrenal paraganglioma
    Jae Im Lee, Su Lim Lee, Kyung Jin Seo
    ANZ Journal of Surgery.2021;[Epub]     CrossRef
  • Laparoscopic resection of a ruptured retroperitoneal paraganglioma
    Shogo Zuo, Toshio Sawai, Hiromichi Kanehiro, Yasuhiro Kuroda, Masayuki Sho
    Journal of Pediatric Surgery Case Reports.2020; 59: 101522.     CrossRef

ACC : Acute and Critical Care