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Korean J Crit Care Med > Volume 26(4); 2011 > Article
Korean Journal of Critical Care Medicine 2011;26(4): 203-207. doi: https://doi.org/10.4266/kjccm.2011.26.4.203
중환자실에서 일어나는 근육 약화
나 성 원ㆍ고 신 옥
연세대학교 의과대학 마취통증의학교실 및 마취통증의학 연구소
ICU Acquired Weakness
Sung Won Na, Shin Ok Koh
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea. sokoh@yuhs.ac
Critical care has focused on recovery from acute organ failure and resuscitation. Neuromuscular abnormalities related to critical illness is not uncommon in critically ill patients, but they were relatively underestimated and unnoticed. Intensive care unit acquired weakness (ICUAW) leading to severe functional impairments in ICU survivors can be divided into two disease entities: critical illness polyneuropathy (CIP) and critical illness myopathy (CIM). Electrophysiologic study, muscle biopsy and physical examination are helpful to diagnose ICUAW. Several researches and reviews identified many risk factors including systemic inflammation, corticosteroids, hyperglycemia, and immobility. Additional research is needed to identify the pathogenesis of this disorder and to testify its preventive or therapeutic modalities.
Key Words: intensive care unit acquired weakness; myopathy; polyneuropathy
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