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2 "Eunhye Bae"
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Original Articles
Pulmonary
Association between timing of intubation and mortality in patients with idiopathic pulmonary fibrosis
Eunhye Bae, Jimyung Park, Sun Mi Choi, Jinwoo Lee, Sang-Min Lee, Hong Yeul Lee
Acute Crit Care. 2022;37(4):561-570.   Published online October 28, 2022
DOI: https://doi.org/10.4266/acc.2022.00444
  • 2,588 View
  • 136 Download
AbstractAbstract PDFSupplementary Material
Background
Delayed intubation is associated with poor prognosis in patients with respiratory failure. However, the effect of delayed intubation in patients with idiopathic pulmonary fibrosis (IPF) remains unknown. This study aimed to analyze whether timing of intubation after high-concentration oxygen therapy was associated with worse clinical outcomes in IPF patients. Methods: This retrospective propensity score-matched study enrolled adult patients with IPF who underwent mechanical ventilation between January 2011 and July 2021. Patients were divided into early and delayed intubation groups. Delayed intubation was defined as use of high-concentration oxygen therapy for at least 48 hours before tracheal intubation. The primary outcome was intensive care unit (ICU) mortality, and a conditional logistic regression model was used to evaluate the association between timing of intubation and clinical outcomes. Results: The median duration of high-concentration oxygen therapy before intubation was 0.5 days in the early intubation group (n=60) and 5.1 days in the delayed intubation group (n=36). The ICU mortality rate was 56.7% and 75% in the early and delayed intubation groups, respectively, before propensity matching (P=0.075). After matching for demographic and clinical covariates, 33 matched pairs were selected. In the propensity-matched cohort, delayed intubation significantly increased the risk of ICU mortality (adjusted odds ratio, 3.99; 95% confidence interval, 1.02–15.63; P=0.046). However, in-hospital mortality did not differ significantly between the groups. Conclusions: In patients with IPF, delayed intubation after initiation of high-concentration oxygen therapy was significantly associated with increased risk of ICU mortality compared to early intubation.
Neurology
Association of natural light exposure and delirium according to the presence or absence of windows in the intensive care unit
Hyo Jin Lee, Eunhye Bae, Hong Yeul Lee, Sang-Min Lee, Jinwoo Lee
Acute Crit Care. 2021;36(4):332-341.   Published online November 26, 2021
DOI: https://doi.org/10.4266/acc.2021.00556
  • 6,657 View
  • 219 Download
  • 10 Web of Science
  • 12 Crossref
AbstractAbstract PDFSupplementary Material
Background
Patients in the intensive care unit (ICU) have increased risks of delirium, which is associated with worse outcomes. As pharmacologic treatments for delirium are ineffective, prevention is important. Nonpharmacologic preventive strategies include exposure to natural light and restoring circadian rhythm. We investigated the effect of exposure to natural light through windows on delirium in the ICU.
Methods
This retrospective cohort study assessed all patients admitted to the medical ICU of a university-affiliated hospital between January and June 2020 for eligibility. The ICU included 12 isolation rooms, six with and six without windows. Patients with ICU stays of >48 hours were included and were divided into groups based on their admission to a single room with (window group) or without windows (windowless group). The primary outcome was the cumulative incidence of delirium. The secondary outcomes were the numbers of delirium- and mechanical ventilation-free days, ICU and hospital length of stay, and in-ICU and 28-day mortalities.
Results
Of the 150 included patients (window group: 83 [55.3%]; windowless group: 67 [44.7%]), the cumulative incidence of delirium was significantly lower in the window group than in the windowless group (21.7% vs. 43.3%; relative risk, 1.996; 95% confidence interval [CI], 1.220–3.265). Other secondary outcomes did not differ between groups. Admission to a room with a window was independently associated with a decreased risk of delirium (adjusted odds ratio, 0.318; 95% CI, 0.125–0.805).
Conclusions
Exposure to natural light through windows was associated with a lower incidence of delirium in the ICU.

Citations

Citations to this article as recorded by  
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    Emergency Medicine Clinics of North America.2024; 42(1): 135.     CrossRef
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    Journal of Surgical Research.2024; 293: 89.     CrossRef
  • The Influence of Exposure to Nature on Inpatient Hospital Stays: A Scoping Review
    Keegan Guidolin, Flora Jung, Sarah Hunter, Han Yan, Marina Englesakis, Stephen Verderber, Sami Chadi, Fayez Quereshy
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    M Harazim
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    Journal of Environmental Psychology.2024; : 102323.     CrossRef
  • Four Decades of Intensive Care Unit Design Evolution and Thoughts for the Future
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    Critical Care Clinics.2023; 39(3): 577.     CrossRef
  • Improving healthcare value: integrating medical practitioners into hospital design in developing countries
    Carlos Machhour Noujeim
    Healthcare in Low-resource Settings.2023;[Epub]     CrossRef
  • Evaluation of the sensory environment in a large tertiary ICU
    Oystein Tronstad, Dylan Flaws, Sue Patterson, Robert Holdsworth, Veronica Garcia-Hansen, Francisca Rodriguez Leonard, Ruth Ong, Stephanie Yerkovich, John F. Fraser
    Critical Care.2023;[Epub]     CrossRef
  • 2021 KSCCM clinical practice guidelines for pain, agitation, delirium, immobility, and sleep disturbance in the intensive care unit
    Yijun Seo, Hak-Jae Lee, Eun Jin Ha, Tae Sun Ha
    Acute and Critical Care.2022; 37(1): 1.     CrossRef
  • Post-acute delirium of COVID-19 infection: Report of two cases
    Dai-Chun Chi, Chih-Pang Chu, TienWei Yang, Hu-Ming Chang
    Taiwanese Journal of Psychiatry.2022; 36(1): 44.     CrossRef
  • The future of intensive care: delirium should no longer be an issue
    Katarzyna Kotfis, Irene van Diem-Zaal, Shawniqua Williams Roberson, Marek Sietnicki, Mark van den Boogaard, Yahya Shehabi, E. Wesley Ely
    Critical Care.2022;[Epub]     CrossRef
  • The effects of hypomagnesemia on delirium in middle-aged and older adult patients admitted to medical intensive care units
    Joong-Yub Kim, Hyo Jin Lee, Hong Yeul Lee, Sang-Min Lee, Jinwoo Lee, Tae Yun Park
    Acute and Critical Care.2022; 37(3): 407.     CrossRef

ACC : Acute and Critical Care