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HOME > Acute Crit Care > Volume 1(1); 1986 > Article
Clinical Study of Patients with Neonatal Respiratory Distress Syndrome

Department of Anesthesioogy and Pediatric *Yonsei University College of Medicine Seoul Korea
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Forty neonates with respiratory distress syndrome were transferred from nursery after birth to the 1CU at Severance Hospital, Yonsei Medical Complex between March 198l to July 1983 and ventilatory support was given with the pressure-cycled ventilator, Baby- log I, Bourns BP 200, in ICU. We have analysed the 40 cases according to sex, incidence, symptoms and signs, birth weight and gestation weeks and time to the ventilator support, 1CU days and mortality. The results were as follows 1) The proportion of the patients was 0.7% neonates and the overall mortality was 52 5% 2) Obstetric and delivery backgrown4 were as follows. Ceasarean section, 19 cases; pre-eclampsia, 5 cases; placenta-previa, 5 cases, spontaneous premature rupture of membrane; 4 cases, 3) The percentage and mortality of male patients was 57.5% and 57,1%, higher than famale patients. 4) All the patients showed symptoms and signs within 12 houre after birth. 5) Mortality of those cases born with less than 32 wks gestation was 15%, but above 32 wks the mortality was 35%. 6) The number of babies born with a birth weight below 2000 grams was 27 and the mortality for them was 70%. 7) The number of cases who had ventilator support begun at 10 hra, 1l-20 and 21- 30 hours after symptoms and signs developed, were 30, 5 and 5. The mortality was 53, 20 and 60% respectively for these 3 groups. 8) The number of ventilator days less than 4 days duration was 27 cases with a 70% mortality but those above 5 days was 13 cases with 16% mortality. In 1981, the number of patients with ventilator days less than 2 days was 11 cases and 2 cases used the ventilator for 7-8 days. But in 1983 the number of patients with less than 4 ventilator days was 6 cases., and 7 cases used ventilator for more than 5 days. 9) The number of patients with ICU days 1ess 5 daye was 23 cases and a morta!ity of 78% and those of 6-10 day stay was 6 cases with a mortality of 50%,. The number of patients with ICU days above 15 days was 18 and a11 survived. In 1981, 10 cases stay in the ICU for less than 5 days. Only 2 cases stayed in the ICU for 6-10 days. In 1983, 6 cases stayed in the ICU for less than 5 days, but 4 cases stayed stayed in the ICU for more than 15 days, 10) Complications were neonatal hyperbilirubinemia, pneumothorax, pneumomediastinum, sepsis, disseminated intravascuIar coagulopathy, bronchopulmonary dysplasia, and cerebraI hemorrhage. From the above results the mortality rate decreased year by year and this is attributed to the early application of ventilator support and adequate intensive care.

ACC : Acute and Critical Care