Acute and Critical Care

Case Report

Thoracic Surgery
Chemical Pleurodesis Using Viscum album Extract in Gorham’s Disease Complicated with Chylothorax: Suk Ju Cho, Su Wan Kim; Acute Crit Care. 2018;33(2):105-109. Published online December 30, 2016; DOI: https://doi.org/10.4266/acc.2016.00164

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Gorham’s disease, also known as massive osteolysis, is characterized by unregulated proliferation of lymphatic or vascular capillaries within bone, resulting in destruction and replacement with angiomatous tissue. This disease can lead to chylothorax that can be lethal. Viscum album extract from European mistletoe is a complementary anti-cancer drug which is commonly prescribed in many European countries and is considered as a new generation of chemical agent for pleurodesis. A 14-year-old girl presented with dyspnea and chest pain. She was diagnosed as Gorham’s disease who was definitively treated with Viscum album extract for chylothorax that was refractory to standard conservative management.

Citations

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Systematic analysis of mistletoe prescriptions in clinical studies
Henrike Staupe, Judith Buentzel, Christian Keinki, Jens Buentzel, Jutta Huebner
Journal of Cancer Research and Clinical Oncology.2023; 149(9): 5559. CrossRef

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