Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo, Egypt
© 2025 The Korean Society of Critical Care Medicine
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CONFLICT OF INTEREST
No potential conflict of interest relevant to this article was reported.
FUNDING
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ACKNOWLEDGMENTS
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AUTHOR CONTRIBUTIONS
All the work was done by Aya Osama Mohamed.
Values are presented as median (interquartile range).
SBP: systolic blood pressure; DBP: diastolic blood pressure; TEMP: temperature; HR: heart rate; RR: respiratory rate; GCS: Glasgow coma scale; pSOFA: pediatric Sequential Organ Failure Assessment; HB: hemoglobin; TLC: total leukocyte count; PLT: platelets; CRP: C-reactive protein; PC: platelet count; PT: prothrombin time; INR: international normalized ratio; PICU: pediatric intensive care unit.
Variable | Non-survivor | Survivor | P-value |
---|---|---|---|
pSOFA score | 7.5 (5.0–11.5) | 4.5 (2.0–8.5) | 0.002 |
Magnesium (mg/dl) | 2.1 (1.9–2.5) | 2.0 (1.8–2.6) | 0.615 |
PICU length of stay days | 8.0 (3.5–13.5) | 6.5 (4.0–11.0) | 0.846 |
OR | 95% CI | P-value | ||
---|---|---|---|---|
pSOFA score as a predictor of mortality | 1.312 | 1.066–1.614 | 0.010 |
Variable | Normal magnesium level | Hypomagnesemia | Hypermagnesemia | P-value |
---|---|---|---|---|
Age (yr) | 2 (1–6) | 2 (1–8) | 1 (0–4) | 0.417 |
SBP (mm Hg) | 88.0 (75.0–100) | 94.5 (78.5–108.5) | 90.0 (80.0–100) | 0.479 |
DBP (mm Hg) | 50.0 (40.0–60.0) | 56.0 (40.0–72.0) | 55.0 (45.0–60.0) | 0.916 |
Temperature (°C) | 38.5 (38.3–39.0) | 38.5 (38.0–39.0) | 38.5 (38.0–39.0) | 0.489 |
HR (beats/min) | 140 (120–160) | 130 (120–155) | 140 (130–150) | 0.823 |
RR (rate/min) | 35.0 (30.0–45.0) | 34.5 (27.0–35.5) | 35.0 (30.0–45.0) | 0.608 |
Capillary refill (sec) | 3 (3–3) | 3 (2.5–3) | 3 (3–3) | 0.630 |
GCS | 14 (10–15) | 15 (14–15) | 15 (11–15) | 0.413 |
pSOFA score | 5.0 (3.0–10.0) | 3.5 (2.0–8.0) | 5.0 (3.0–9.0) | 0.692 |
Hemoglobin (g/dl) | 10.0 (8.6–11.6) | 8.1 (6.6–9.45) | 9.95 (8.9–10.9) | 0.219 |
TLC (/μl of blood) | 17.6 (10.9–21.0) | 6.7 (4.3–34.0) | 17.9 (14.0–24.0) | 0.297 |
PLT (/μl of blood) | 345.0 (173–435) | 160.0 (104–544) | 324.5 (155–433) | 0.780 |
CRP (mg/dl) | 48.0 (6.0–170.0) | 24.0 (0–72.0) | 12.0 (0–96.0) | 0.043 |
Platelet count (%) | 54.0 (40.5–68.5) | 42.5 (40.0–45.0) | 54.0 (41.0–70.0) | 0.509 |
PT (sec) | 18.2 (15.9–26.0) | 19.5 (18.0–21.0) | 17.0 (14.0–19.8) | 0.366 |
INR | 1.4 (1.3–2.0) | 1.75 (1.6–1.9) | 1.4 (1.3–1.7) | 0.521 |
pH | 7.36 (7.30–7.42) | 7.40 (7.35–7.50) | 7.35 (7.22–7.42) | 0.436 |
PCO2 (mm Hg) | 33.0 (26.0–37.0) | 20.5 (20.0–21.0) | 35.0 (30.0–41.0) | 0.089 |
HCO3 (mmol/L) | 19.0 (15.7–23.0) | 16.5 (11.0–22.0) | 19.0 (14.0–24.0) | 0.898 |
Na (mmol/L) | 137.0 (134.0–144.0) | 143.0 (140.0–157.0) | 141.5 (136.0–149.0) | 0.07 |
K (mmol/L) | 4.5 (3.9–5.1) | 3.7 (2.9–4.5) | 4.4 (3.3–4.9) | 0.301 |
PICU length of stay (day) | 7.0 (3.0–12.0) | 5.5 (3.0–9.5) | 7.0 (5.0–13.0) | 0.659 |
Variable | Normal magnesium level | Hypomagnesemia | Hypermagnesemia | P-value | |
---|---|---|---|---|---|
Diagnosis | |||||
Sex | 0.402 | ||||
Female | 15 (36.6) | 1 (25.0) | 16 (51.6) | ||
Male | 26 (63.4) | 3 (75.0) | 15 (48.4) | ||
Gastroenteritis | 2 (4.9) | 1 (25.0) | 1 (3.2) | 0.302 | |
Encephalopathy | 1 (2.4) | - | 5 (16.1) | 0.126 | |
Acute renal injury | 3 (7.3) | - | 1 (3.2) | 0.703 | |
Diabetic ketoacidosis | 2 (4.9) | - | 3 (9.7) | 0.732 | |
Pneumonia | 11 (26.8) | - | 7 (22.6) | 0.673 | |
Cardiogenic shock | 2 (4.9) | - | - | 0.554 | |
Coagulopathy | 2 (4.9) | - | - | 0.554 | |
GBS | 1 (2.4) | - | 1 (3.2) | 1.000 | |
Heart failure | 1 (2.4) | - | 3 (9.7) | 0.445 | |
Autoimmune encephalitis | 1 (2.4) | - | 1.000 | ||
Clinical course | |||||
Need for MV | 15 (36.6) | 1 (25.0) | 6 (19.4) | 0.899 | |
Need for inotropes | 16 (39.0) | 1 (25.0) | 10 (32.3) | 1.000 | |
Mortality | 16 (39.0) | - | 12 (38.7) | 0.415 | |
Mortality | Survivor | Non-survivor | |||
Need for MV | 10 (2.8) | 12 (42.9) | 0.041 | ||
Need for inotropes | 13 (27.1) | 14 (50.0) | 0.044 |
Variable | Non-survivor | Survivor | P-value |
---|---|---|---|
pSOFA score | 7.5 (5.0–11.5) | 4.5 (2.0–8.5) | 0.002 |
Magnesium (mg/dl) | 2.1 (1.9–2.5) | 2.0 (1.8–2.6) | 0.615 |
PICU length of stay days | 8.0 (3.5–13.5) | 6.5 (4.0–11.0) | 0.846 |
OR | 95% CI | P-value | ||
---|---|---|---|---|
pSOFA score as a predictor of mortality | 1.312 | 1.066–1.614 | 0.010 |
Values are presented as median (interquartile range). SBP: systolic blood pressure; DBP: diastolic blood pressure; TEMP: temperature; HR: heart rate; RR: respiratory rate; GCS: Glasgow coma scale; pSOFA: pediatric Sequential Organ Failure Assessment; HB: hemoglobin; TLC: total leukocyte count; PLT: platelets; CRP: C-reactive protein; PC: platelet count; PT: prothrombin time; INR: international normalized ratio; PICU: pediatric intensive care unit.
Values are presented as number (%). GBS: Guillain barre syndrome; MV: mechanical ventilator.
Values are presented as median (interquartile range). pSOFA: pediatric Sequential Organ Failure Assessment; PICU: pediatric intensive care unit.
OR: odds ratio; pSOFA: pediatric Sequential Organ Failure Assessment.