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Neurology/Pulmonary
Extensive and Progressive Cerebral Infarction after Mycoplasma pneumoniae Infection
Yu Hyeon Choi, Hyung Joo Jeong, Bongjin Lee, Hong Yul An, Eui Jun Lee, June Dong Park
Korean J Crit Care Med. 2017;32(2):211-217.   Published online December 29, 2016
DOI: https://doi.org/10.4266/kjccm.2016.00283
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  • 3 Web of Science
  • 3 Crossref
AbstractAbstract PDF
Acute cerebral infarctions are rare in children; however they can occur as a complication of a Mycoplasma pneumoniae (MP) infection due to direct invasion, vasculitis, or a hypercoagulable state. We report on the case of a 5-year-old boy who had an extensive stroke in multiple cerebrovascular territories 10 days after the diagnosis of MP infection. Based on the suspicion that the cerebral infarction was associated with a macrolide-resistant MP infection, the patient was treated with levofloxacin, methyl-prednisolone, intravenous immunoglobulin, and enoxaparin. Despite this medical management, cerebral vascular narrowing progressed and a decompressive craniectomy became necessary for the patient’s survival. According to laboratory tests, brain magnetic resonance imaging, and clinical manifestations, the cerebral infarction in this case appeared to be due to the combined effects of hypercoagulability and cytokine-induced vascular inflammation.

Citations

Citations to this article as recorded by  
  • Stroke associated with Mycoplasma hominis infection: a case report
    Anthoula C. Tsolaki, Galaktion Konstantinidis, Stavroula Koukou, Fotini Michali, Despina Georgiadou, Thomas Tegos, Nikolaos D. Michalis
    Journal of Medical Case Reports.2021;[Epub]     CrossRef
  • Thrombosis associated with mycoplasma pneumoniae infection (Review)
    Jingwei Liu, Yumei Li
    Experimental and Therapeutic Medicine.2021;[Epub]     CrossRef
  • Multiple anatomic sites of infarction in a pediatric patient with M. pneumoniae infection, a case report
    Devon W. Hahn, Claire E. Atkinson, Matthew Le
    BMC Pediatrics.2021;[Epub]     CrossRef

ACC : Acute and Critical Care