Acute and Critical Care

Original Articles

Epidemiology
Post-traumatic stress disorder, anxiety, and depression in North African intensive care unit survivors: a prospective observational study: Imen Ben Saida, Marwa Zghidi, Safa Fathallah, Mohamed Boussarsar; Acute Crit Care. 2025;40(3):402-412. Published online August 29, 2025; DOI: https://doi.org/10.4266/acc.000150

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Background
Survivors of critical illness often face significant physical and psychological challenges, including post-traumatic stress disorder (PTSD), anxiety, and depression, which can severely impact their quality of life. This study aimed to evaluate the prevalence and associated factors of PTSD, anxiety, and depression among intensive care unit (ICU) survivors 3 months after discharge, and investigate the prevalence and determinants of post-intensive care syndrome–related neuropsychiatric disorders (PICS-ND).
Methods
This is a prospective observational analytical study carried out in a medical ICU. Three months after discharge from the ICU, survivors were contacted by telephone to complete the Impact Event Scale-Revised and Hospital Anxiety and Depression Scale questionnaires. Univariate and multivariate analyses were performed to identify variables that were independently and significantly associated with outcomes.
Results
A total of 114 survivors was enrolled. At 3 months, PTSD, anxiety, and depression were prevalent in 21.9%, 21.0%, and 9.6% of patients, respectively. Associated factors were younger age, female, physical restraint, and critical illness polyneuropathy and myopathy (CIPNM) for PTSD; unmarried, low Charlson index, and physical restraint for anxiety; and younger age and CIPNM for depression. PICS-ND, a composite measure of neuropsychiatric morbidity, was present in 28.9% of patients, with younger age, female, and physical restraint identified as associated factors.
Conclusions
PTSD, anxiety, depression, and PICS-ND were common among ICU survivors at 3 months. Various factors, including younger age, female, unmarried, lower Charlson index, physical restraint, and CIPNM, were associated with these psychological outcomes.

Citations

Citations to this article as recorded by

Effect of high-dose baclofen on post-traumatic stress disorder symptoms five years after hospitalization among critically ill patients with unhealthy alcohol use
Marwan Bouras, Karim Asehnoune, Yann Robert-Valli, Pierre-Joachim Mahe, Jean Reignier, Adel Maamar, Jean-Claude Lacherade, Maud Jonas, Boris Jung, Martine Ferrandiere, Samir Jaber, Laurent Flet, Mikael Moriconi, Sigismond Lasocki, Roland Smonig, Christoph
Scientific Reports.2026;[Epub] CrossRef
Traumatic memories and nursing experiences of ICU discharged patients: a systematic review and meta-synthesis of qualitative studies
Ting Li, Ying Wu, Rui Li, Shuyan Wang
BMC Nursing.2026;[Epub] CrossRef

Epidemiology
Hearing screening outcomes in pediatric critical care survivors: a 1-year report: Pattita Suwannatrai, Chanapai Chaiyakulsil; Acute Crit Care. 2022;37(2):209-216. Published online March 8, 2022; DOI: https://doi.org/10.4266/acc.2021.00899

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171 Download
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Abstract PDF

Background
Hearing loss is a potentially serious complication that can occur after surviving a critical illness. Study on screening for hearing problems in pediatric critical care survivors beyond the neonatal period is lacking. This study aimed to identify the prevalence of abnormal hearing screening outcomes using transitory evoked otoacoustic emission (TEOAE) screening in children who survived critical illness and to find possible associating factors for abnormal hearing screening results.
Methods
This study was a single-center, prospective, observational study. All children underwent otoscopy to exclude external and middle ear abnormalities before undergoing TEOAE screening. The screening was conducted before hospital discharge. Descriptive statistics, chi-square, and logistic regression tests were used for data analysis.
Results
A total of 92 children were enrolled. Abnormal TEOAE responses were identified in 26 participants (28.3%). Children with abnormal responses were significantly younger than those with normal responses with a median age of 10.0 months and 43.5 months, respectively (P<0.001). Positive association with abnormal responses was found in children younger than 12 months of age (adjusted odds ratio [OR], 3.07; 95% confidence interval [CI], 1.06–8.90) and children with underlying genetic conditions (adjusted OR, 6.95; 95% CI, 1.49–32.54).
Conclusions
Our study demonstrates a high prevalence of abnormal TEOAE screening responses in children surviving critical illness, especially in patients younger than 12 months of age. More extensive studies should be performed to identify the prevalence and associated risk factors of hearing problems in critically ill children.

Citations

Citations to this article as recorded by

Hearing loss assessment by pure tone audiometry amongst the survivors of intensive care unit: A prospective observational cohort study
Sai Saran, Abhishek Bahadur Singh, Avinash Agrawal, Saumitra Misra, Suhail Sarwar Siddiqui, Ayush Lohiya, Prabhaker Misra
Journal of Critical Care.2025; 87: 155042. CrossRef
Hearing Deficits Assessment by Pure Tone Audiometry Amongst the Survivors of Intensive Care Unit: A Prospective Observational Cohort Study
Avinash Agrawal, Suhail Sarwar Siddiqui, Sai Saran, Saumitra Misra, Abhishek Bahadur Singh
Indian Journal of Critical Care Medicine.2025; 29(S1): S126. CrossRef
Physiological and electrophysiological evaluation of the hearing system in low birth weight neonates treated with cholestin: a cohort study
Nastaran Khosravi, Malihah Mazaheryazdi, Majid Kalani, Nasrin Khalesi, Zinat Shakeri, Saeedeh Archang, Maryam Archang
The Egyptian Journal of Otolaryngology.2023;[Epub] CrossRef

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