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2 "neuroleptic malignant syndrome"
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Clozapine Induced Neuroleptic Malignant Syndrome
Yong Suk Jo, Hyung Ah Jo, Byung Chul Yu, Jung Hoon Shin, Kook-Hwan Oh
Korean J Crit Care Med. 2017;32(3):291-294.   Published online December 29, 2016
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AbstractAbstract PDF
Neuroleptic malignant syndrome is a rare, but potentially life-threatening adverse event associated with the use of neuroleptic agents. We describe the case of a 47-year-old schizophrenic woman who was treated with clozapine for years. The patient developed acute renal failure with pulmonary edema, and underwent mechanical ventilation and hemodialysis.
Malignant Neuroleptic Syndrome following Deep Brain Stimulation Surgery of Globus Pallidus Pars Internus in Cerebral Palsy
Jae Meen Lee, Sun Ha Paek, Hye Ran Park, Kang Hee Lee, Chae Won Shin, Hye Young Park, Hee Pyoung Park, Dong Gyu Kim, Beom Seok Jeon
Korean J Crit Care Med. 2016;31(1):34-38.   Published online February 29, 2016
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  • 1 Citations
AbstractAbstract PDF
Neuroleptic malignant syndrome (NMS) is a rare but potentially lethal outcome caused by sudden discontinuation or dose reduction of dopaminergic agents. We report an extremely rare case of NMS after deep brain stimulation (DBS) surgery in a cerebral palsy (CP) patient without the withdrawal of dopaminergic agents. A 19-year-old girl with CP was admitted for DBS due to medically refractory dystonia and rigidity. Dopaminergic agents were not stopped preoperatively. DBS was performed uneventfully under monitored anesthesia. Dopaminergic medication was continued during the postoperative period. She manifested spasticity and muscle rigidity, and was high fever resistant to anti-pyretic drugs at 2 h postoperative. At postoperative 20 h, she suffered cardiac arrest and expired, despite vigorous cardiopulmonary resuscitation. NMS should be considered for hyperthermia and severe spasticity in CP patients after DBS surgery, irrespective of continued dopaminergic medication.


Citations to this article as recorded by  
  • Metal-free carboxyl modified g-C3N4 for enhancing photocatalytic degradation activity of organic pollutants through peroxymonosulfate activation in wastewater under solar radiation
    Xueting Mei, Shujun Chen, Gangqiang Wang, Wenxing Chen, Wangyang Lu, Bingying Zhang, Yu Fang, Chenxiao Qi
    Journal of Solid State Chemistry.2022; 310: 123053.     CrossRef

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