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Review Article
- CPR/Resuscitation
- Beyond blood pressure: a comprehensive overview of clinical indices in shock and tissue hypoperfusion
- Jooyun Kim, Saeyeon Kim, Ji-Hee Lee, Sua Kim
- Acute Crit Care. 2026;41(2):201-212. Published online May 28, 2026
- DOI: https://doi.org/10.4266/acc.003425
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Abstract
PDF - Shock is a state of circulatory failure characterized by impaired tissue perfusion due to a mismatch between oxygen delivery and consumption. While macrocirculation serves as a conduit to sustain blood flow toward the microcirculatory networks, it is the microcirculation that ultimately ensures the delivery of oxygen and nutrients to maintain cellular and organ function. The maintenance of proper macrocirculation is essential, but it does not necessarily indicate adequate microcirculation or recovery from shock. Thus, assessment of the microcirculation is also required to confirm effective tissue oxygenation. A comprehensive evaluation of both circulatory levels is crucial for accurate diagnosis and prognostication in patients with shock. This review explores a diverse range of clinical, biochemical, and device-based indicators that reflect the perfusion status of patients in shock. By examining their physiological significance and clinical relevance, we aim to provide a comprehensive framework for the hemodynamic assessment of critically ill patients and support the use of multidimensional strategies in shock management.
Case Report
- Induced Hypertension Using Phenylephrine in Patients with Acute Ischemic Stroke: A Case Report
- Sang Beom Jeon, Hoyon Sohn
- Korean J Crit Care Med. 2010;25(3):172-175.
- DOI: https://doi.org/10.4266/kjccm.2010.25.3.172
- 6,360 View
- 139 Download
- 1 Crossref
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Abstract
PDF
- Decreased cerebral perfusion is associated with a poor prognosis for a patient suffering from acute ischemic stroke. Induced hypertension may improve the cerebral perfusion and stroke symptoms. However, there is not enough clinical evidence to support this therapy and it is rarely performed in daily practice. Here we report three patients with acute ischemic stroke and cerebral hypoperfusion who were successfully treated with induced hypertension using intravenous phenylephrine. Phenylephrine infusion may be a treatment option for patients suffering from acute ischemic stroke and cerebral hypoperfusion.
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Citations
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- Therapeutic Use and Chronic Abuse of CNS Stimulants and Anabolic Drugs
Daniela Coliță, Cezar-Ivan Coliță, Dirk Hermann, Eugen Coliță, Thorsten Doeppner, Ion Udristoiu, Aurel Popa-Wagner
Current Issues in Molecular Biology.2022; 44(10): 4902. CrossRef
- Therapeutic Use and Chronic Abuse of CNS Stimulants and Anabolic Drugs
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