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Original Article
Pediatrics
A deep learning model for estimating sedation levels using heart rate variability and vital signs: a retrospective cross-sectional study at a center in South Korea
You Sun Kim, Bongjin Lee, Wonjin Jang, Yonghyuk Jeon, June Dong Park
Acute Crit Care. 2024;39(4):621-629.   Published online November 25, 2024
DOI: https://doi.org/10.4266/acc.2024.01200
Retraction in: Acute Crit Care 2025;40(3):512
  • 6,578 View
  • 40 Download
  • 3 Web of Science
  • 2 Crossref
Randomized Controlled Trial
Optimal Timing of Topical Lidocaine Spray on the Hemodynamic Change of Tracheal Intubation
Keun Seok Lee, Hyun Jung Shin, Yang Ju Tak, Sang Tae Kim
Korean J Crit Care Med. 2011;26(2):89-93.
DOI: https://doi.org/10.4266/kjccm.2011.26.2.89
  • 5,129 View
  • 85 Download
AbstractAbstract PDF
BACKGROUND
Tracheal intubation stimulates the sympathetic nervous system, resulting in hypertension, tachycardia and sometimes critical complications, especially in patients with underlying hypertension, cardiovascular disease or cerebrovascular disease. In this study, we sprayed 4% lidocaine into the trachea before intubation, and observed the hemodynamic changes after tracheal intubation.
METHODS
We randomly allocated 87 patients, whose ASA physical status was I or II, into three groups. The 4% topical lidocaine was sprayed before intubation at the following specific times: just before intubation (group 0), or 1 minute (group 1) and 2 minutes before intubation (group 2). For maintenance of anesthesia, TIVA (total intravenous anesthesia; propofol-remifentanil infusion with orchestra(R)) was used. We observed hemodynamic changes between the groups just after the intubation, as well as 1, 3 and 5 minutes after the intubation. Hemodynamic changes were also monitored in the same group.
RESULTS
When the patients arrived at the operating room, we found no significant difference in heart rate and arterial pressure between the groups. However, heart rate after intubation in group 1 was significantly lower than group 0. The diastolic and mean arterial pressure just after intubation were lower in group 1 and 2 than in group 0.
CONCLUSIONS
Spraying lidocaine 1 or 2 minutes before intubation was more effective than spraying it just before intubation for reducing hypertensive responses after intubation.
Original Article
Nonlinear Analysis of Heart Rate Variability: Possible Predictor for Atrial Fibrillation after Coronary Artery Bypass Graft (CABG) Surgery
Kyung Sil Im, Jong Bun Kim, Jae Myeong Lee, Kuhn Park, Hyun Ju Jung, Jeong Yun Rhee
Korean J Crit Care Med. 2007;22(1):25-29.
  • 2,591 View
  • 71 Download
AbstractAbstract PDF
BACKGROUND
Heart Rate Variability (HRV) is a valuable marker of autonomic tone and may assist evaluating the prognosis in patients with heart disease. The purpose of this study was to assess whether preoperative heart rate variability analysis predicts atrial fibrillation in patients undergoing coronary artery bypass graft (CABG) surgery. METHODS: This study was designed as a prospective observational study. After IRB approval was obtained by our institution, 76 patients scheduled for elective CABG surgery underwent a 10-min electrocardiogram recordings 1~2 hours prior to surgery. Heart rate variability analysis was performed with spectral analysis and point correlation dimension. RESULTS: There was no significant difference in the low and high frequency component (LF/HF) ratio preoperatively between patients with atrial fibrillation and patients with normal sinus rhythm postoperatively (3.0+/-2.45, 4.25+/-3.70, p=0.085). Baseline peak point correlation dimension (pPD2) was significantly higher in patients with atrial fibrillation than in patients with normal sinus rhythm postoperatively (4.2+/-0.8, 3.8+/-0.7, p=0.042). CONCLUSIONS: Patients who developed atrial fibrillation postoperatively had a higher baseline pPD2 value preoperatively. Point correlation dimensions may predict the occurrence of postoperative atrial fibrillation after CABG surgery. However, further studies are needed to confirm whether point correlation dimensions are an effective predictor for postoperative atrial fibrillation.

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