Acute and Critical Care

Case Report

Infection
The first case of abdominal mycotic aneurysm caused by K1 hypervirulent Klebsiella pneumoniae in a healthy adult: Misun Kim, Jeong Rae Yoo, Hyunjoo Oh, Young Ree Kim, Keun Hwa Lee, Sang Taek Heo; Acute Crit Care. 2021;36(4):390-394. Published online November 16, 2021; DOI: https://doi.org/10.4266/acc.2021.00010

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Incidence of hypervirulent Klebsiella pneumoniae (hvKp) infection has been steadily increasing in the Asia-Pacific rim. The characteristic of hvKp infection is its ability to cause multiple site infections and unpredictable metastatic spread in the community. We describe the first case of mycotic aneurysm caused by hvKp serotype K1 in a previously healthy man and review the literature. Of a total of 13 cases, including our case, three cases were related to hvKp. Among patients with hvKp, the level of mycotic aneurysm in most patients was the infrarenal aorta, and they underwent an aortic graft or coil embolization. All strains were susceptible to most antimicrobial agents, except ampicillin. Early detection of hvKp can help to prevent the metastatic spread of pathogens and be useful for optimal patient care and epidemiologic research.

Citations

Citations to this article as recorded by

Designing a conjugate vaccine targeting Klebsiella pneumoniae ST258 and ST11
Min Li, Mingkai Yu, Yigang Yuan, Danyang Li, Daijiao Ye, Min Zhao, Zihan Lin, Liuzhi Shi
Heliyon.2024; 10(5): e27417. CrossRef
Klebsiella Pneumoniae Invasive Syndrome With Thoracic Aortic Pseudoaneurysm
Kosuke Tsuda, Hideaki Morita, Chiaki Hikida, Kanako Akamatsu, Hideki Ozawa, Yumiko Kanzaki, Yoshihiko Arima, Hiroaki Uchida, Isao Morii, Masaya Kino, Takahiro Katsumata, Masaaki Hoshiga
Circulation: Cardiovascular Imaging.2024;[Epub] CrossRef
Successful treatment of acute respiratory distress syndrome caused by hypervirulent Klebsiella pneumoniae with extracorporeal membrane oxygenation and continuous renal replacement therapy: A case report and literature review
Wenzhong Peng, Yanhao Wu, Rongli Lu, Yunpeng Zheng, Jie Chen, Pinhua Pan
Frontiers in Medicine.2022;[Epub] CrossRef
Gut microbiome sheds light on the development and treatment of abdominal aortic aneurysm
Xuebin Ling, Wei Jie, Xue Qin, Shuya Zhang, Kaijia Shi, Tianfa Li, Junli Guo
Frontiers in Cardiovascular Medicine.2022;[Epub] CrossRef

Review Article

Hematology
Severe Fever with Thrombocytopenia Syndrome: Seung Jin Yoo, Sang Taek Heo, Keun Hwa Lee; Korean J Crit Care Med. 2014;29(2):59-63. Published online May 31, 2014; DOI: https://doi.org/10.4266/kjccm.2014.29.2.59

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Abstract PDF

Severe fever with thrombocytopenia syndrome (SFTS) is a newly emerging infectious disease, caused by a novel species of Phlebovirus of Bunyaviridae family, in China, South Korea, and Japan. SFTS is primarily known as a tick-borne disease, and human-to-human transmission is also possible in contact with infectious blood. Common clinical manifestations include fever, thrombocytopenia, and leukopenia as initial symptoms, and multiple organ dysfunction and failure manifest with disease progression. Whereas disease mortality is reported to be 12% to 30% in China, a recent report of cumulative SFTS cases indicated 47% in Korea. Risk factors associated with SFTS were age, presence of neurologic disturbance, serum enzyme levels, and elevated concentrations of certain cytokines. Diagnosis of SFTS is based on viral isolation, viral identification by polymerase chain reaction, and serologic identification of specific immunoglobulin G. Therapeutic guideline has not been formulated, but conservative management is the mainstream of treatment to prevent disease progression and fatal complications.

Citations

Citations to this article as recorded by

The first discovery of severe fever with thrombocytopenia syndrome virus in Taiwan
Tsai-Lu Lin, Shan-Chia Ou, Ken Maeda, Hiroshi Shimoda, Jacky Peng-Wen Chan, Wu-Chun Tu, Wei-Li Hsu, Chi-Chung Chou
Emerging Microbes & Infections.2020; 9(1): 148. CrossRef
Epidemiology of severe fever and thrombocytopenia syndrome virus infection and the need for therapeutics for the prevention
Norbert John C. Robles, Hae Jung Han, Su-Jin Park, Young Ki Choi
Clinical and Experimental Vaccine Research.2018; 7(1): 43. CrossRef
Two Treatment Cases of Severe Fever and Thrombocytopenia Syndrome with Oral Ribavirin and Plasma Exchange
In Park, Hye In Kim, Ki Tae Kwon
Infection & Chemotherapy.2017; 49(1): 72. CrossRef

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