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5 "In-Ae Song"
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Editorial
Ethics
Will implementation of the Life-sustaining Treatment Decisions Act reduce the incidence of cardiopulmonary resuscitation?
In-Ae Song
Acute Crit Care. 2022;37(2):256-257.   Published online May 30, 2022
DOI: https://doi.org/10.4266/acc.2022.00668
  • 2,011 View
  • 136 Download
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Review Article
Basic science and research
Review of remimazolam and sedatives in the intensive care unit
Hey-Ran Choi, In-Ae Song
Acute Crit Care. 2022;37(2):151-158.   Published online May 30, 2022
DOI: https://doi.org/10.4266/acc.2022.00619
  • 5,431 View
  • 363 Download
  • 2 Web of Science
  • 4 Crossref
AbstractAbstract PDF
Remimazolam is a novel intravenous ultra-short acting benzodiazepine that has the potential of being a safe and effective new sedative for use in intensive care unit (ICU) settings. Because remimazolam metabolizes rapidly by being hydrolyzed to an inactive metabolite (CNS 7054) through non-specific tissue esterase activity, specific dosing adjustment for older adults and for patients with renal or hepatic impairment patients (except for those with severe hepatic impairment) is not required. In addition, research has shown that remimazolam may be reversed by administration of flumazenil, as its half time was sufficiently short compared to flumazenil. It shows a lower incidence of cardiorespiratory depression, less injection pain, and no fatal complications such as propofol infusion syndrome and malignant hyperthermia of inhalational anesthetics. Future studies to study the suitability of remimazolam for managing the sedation of ICU patients who need sedation for a long time over several days is required.

Citations

Citations to this article as recorded by  
  • Remimazolam: A New Ingress in Cardiac Surgical Intensive Care Unit
    Minati Choudhury, Poonam Malhotra Kapoor
    Journal of Cardiac Critical Care TSS.2023; 7: 133.     CrossRef
  • Safety and efficacy of remimazolam tosilate combined with low-dose fentanyl for procedural sedation in obese patients undergoing gastroscopy: study protocol for a single-centre, double-blind, randomised controlled trial
    Lijuan Yan, Xiao Wang, Zhenyi Chen, Ningning Wu, Hao Li, Bin Yang
    BMJ Open.2023; 13(12): e079095.     CrossRef
  • Remimazolam: An Updated Review of a New Sedative and Anaesthetic
    Qinxue Hu, Xing Liu, Chengli Wen, Duo Li, Xianying Lei
    Drug Design, Development and Therapy.2022; Volume 16: 3957.     CrossRef
  • Análisis nacional de la sedación aplicada en pacientes de cuidados críticos
    Grace Pamela López Pérez, Melani Dayana Carrera Casa, Gissela Lizbeth Amancha Moyulema, Yadira Nathaly Chicaiza Quilligana, Ana Belén Guamán Tacuri, Joselyn Mireya Iza Arias
    Salud, Ciencia y Tecnología.2022; 2(S1): 234.     CrossRef
Original Articles
Surgery
Association of Immediate Postoperative Temperature in the Surgical Intensive Care Unit with 1-Year Mortality: Retrospective Analysis Using Digital Axillary Thermometers
Jiwook Kim, Tak Kyu Oh, Jaebong Lee, Saeyeon Kim, In-Ae Song
Acute Crit Care. 2019;34(1):53-59.   Published online January 9, 2019
DOI: https://doi.org/10.4266/acc.2019.00255
  • 6,423 View
  • 125 Download
  • 4 Web of Science
  • 5 Crossref
AbstractAbstract PDFSupplementary Material
Background
Postoperative body temperature is closely associated with prognosis although there is limited research regarding this association at postoperative intensive care unit (ICU) admission. Furthermore, no studies have used digital axillary thermometers to measure postoperative body temperature. This study investigated the association between mortality and postoperative temperature measured using a digital axillary thermometer within 10 minutes after ICU admission. Methods: This retrospective observational study evaluated data from adult patients admitted to an ICU after elective or emergency surgery. The primary outcome was 1-year mortality after ICU admission. Multivariable logistic regression analysis with restricted cubic splines was used to evaluate the association between temperature and outcomes. Results: We evaluated data from 5,868 patients admitted between January 1, 2013 and May 31, 2016, including 5,311 patients (90.5%) who underwent noncardiovascular surgery and 557 patients (9.5%) who underwent cardiovascular surgery. Deviation from the median temperature (36.6°C) was associated with increases in 1-year mortality (≤ 36.6°C: linear coefficient, –0.531; P<0.001 and ≥36.6°C: spline coefficient, 0.756; P<0.001). Similar statistically significant results were observed in the noncardiovascular surgery group, but not in the cardiovascular surgery group. Conclusions: An increase or decrease in body temperature (vs. 36.6°C) measured using digital axillary thermometers within 10 minutes of postoperative ICU admission was associated with increased 1-year mortality. However, no significant association was observed after cardiovascular surgery. These results suggest that postoperative temperature is associated with longterm mortality in patients admitted to the surgical ICU in the postoperative period.

Citations

Citations to this article as recorded by  
  • Construction of a nursing assessment framework for patients in anaesthesia recovery period: A modified Delphi study
    Lang Peng, Xianxian Zang, Ruili Liu, Ping Bai, Lu Wang, Guoyong Yang
    Journal of Advanced Nursing.2024;[Epub]     CrossRef
  • A prognostic model for 1-month mortality in the postoperative intensive care unit
    Mohammad Fathi, Nader Markazi Moghaddam, Saba Naderian Jahromi
    Surgery Today.2022; 52(5): 795.     CrossRef
  • Relationship Between First 24-h Mean Body Temperature and Clinical Outcomes of Post-cardiac Surgery Patients
    Fei Xu, Cheng Zhang, Chao Liu, Siwei Bi, Jun Gu
    Frontiers in Cardiovascular Medicine.2021;[Epub]     CrossRef
  • Rebound hypothermia after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) and cardiac arrest in immediate postoperative period: a report of two cases and review of literature
    Sohan Lal Solanki, Mrida A. K. Jhingan, Avanish P. Saklani
    Pleura and Peritoneum.2020;[Epub]     CrossRef
  • Postoperative Hypothermia
    Deokkyu Kim
    Acute and Critical Care.2019; 34(1): 79.     CrossRef
Pediatrics
Impact of Socioeconomic Status on 30-Day and 1-Year Mortalities after Intensive Care Unit Admission in South Korea: A Retrospective Cohort Study
Tak Kyu Oh, Jihoon Jo, Young-Tae Jeon, In-Ae Song
Acute Crit Care. 2018;33(4):230-237.   Published online November 13, 2018
DOI: https://doi.org/10.4266/acc.2018.00514
  • 6,771 View
  • 96 Download
  • 6 Web of Science
  • 6 Crossref
AbstractAbstract PDFSupplementary Material
Background
Socioeconomic status (SES) is closely associated with health outcomes, including mortality in critically ill patients admitted to intensive care unit (ICU). However, research regarding this issue is lacking, especially in countries where the National Health Insurance System is mainly responsible for health care. This study aimed to investigate how the SES of ICU patients in South Korea is associated with mortality.
Methods
This was a retrospective observational study of adult patients aged ≥20 years admitted to ICU. Associations between SES-related factors recorded at the time of ICU admission and 30-day and 1-year mortalities were analyzed using univariable and multivariable Cox regression analyses.
Results
A total of 6,008 patients were included. Of these, 394 (6.6%) died within 30 days of ICU admission, and 1,125 (18.7%) died within 1 year. Multivariable Cox regression analysis found no significant associations between 30-day mortality after ICU admission and SES factors (P>0.05). However, occupation was significantly associated with 1-year mortality after ICU admission.
Conclusions
Our study shows that 30-day mortality after ICU admission is not associated with SES in the National Health Insurance coverage setting. However, occupation was associated with 1-year mortality after ICU admission.

Citations

Citations to this article as recorded by  
  • Association Between Socioeconomic Status and Outcomes in Critical Care: A Systematic Review and Meta-Analysis
    Ryan D. McHenry, Christopher E. J. Moultrie, Tara Quasim, Daniel F. Mackay, Jill P. Pell
    Critical Care Medicine.2023; 51(3): 347.     CrossRef
  • The effect of socioeconomic status, insurance status, and insurance coverage benefits on mortality in critically ill patients admitted to the intensive care unit
    Moo Suk Park
    Acute and Critical Care.2022; 37(1): 118.     CrossRef
  • Association between off-hour admission of critically ill children to intensive care units and mortality in a Japanese registry
    Takahiro Kido, Masao Iwagami, Toshikazu Abe, Yuki Enomoto, Hidetoshi Takada, Nanako Tamiya
    Scientific Reports.2021;[Epub]     CrossRef
  • Associations Between Socioeconomic Status, Patient Risk, and Short-Term Intensive Care Outcomes
    Daniel V. Mullany, David V. Pilcher, Annette J. Dobson
    Critical Care Medicine.2021; 49(9): e849.     CrossRef
  • Association of Economic Status and Mortality in Patients with Acute Respiratory Distress Syndrome
    Tak Kyu Oh, In-Ae Song, Jae Ho Lee
    International Journal of Environmental Research and Public Health.2020; 17(6): 1815.     CrossRef
  • Critical Care Research Using “Big Data”: A Reality in the Near Future
    Kwangha Lee
    Acute and Critical Care.2018; 33(4): 269.     CrossRef
Letter to the Editor
Ethics
Should Very Old Patients Be Admitted to the Intensive Care Units?
Jun Kwon Cha, In-Ae Song
Korean J Crit Care Med. 2017;32(4):376-377.   Published online November 30, 2017
DOI: https://doi.org/10.4266/kjccm.2017.00521
  • 5,360 View
  • 143 Download
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ACC : Acute and Critical Care