Skip Navigation
Skip to contents

ACC : Acute and Critical Care


Author index

Page Path
HOME > Issue > Author index
Minh Cuong Duong 1 Article
Predictive value of the negative inspiratory force index as a predictor of weaning success: a crosssectional study
Phuong Hoang Vu, Viet Duc Tran, Minh Cuong Duong, Quyet Thang Cong, Thu Nguyen
Acute Crit Care. 2020;35(4):279-285.   Published online November 30, 2020
  • 6,829 View
  • 689 Download
  • 2 Web of Science
  • 4 Crossref
AbstractAbstract PDF
Identifying when intubated patients are ready to be extubated remains challenging. The negative inspiratory force (NIF) is a recommended predictor of weaning success. However, little is known about the role of NIF in the weaning process for the Asian surgical intensive population, especially for the Vietnamese population. Here, we aimed to investigate the cutoff threshold and predictive value of the NIF index for predicting the success of ventilator weaning in Vietnamese surgical intensive care patients.
A cross-sectional study was conducted at the Surgical Intensive Care Unit of Viet Duc Hospital from October 2016 to August 2017. A total of 64 patients aged 16–70 years undergoing ventilatory support through an orotracheal tube satisfied the criteria for readiness to begin weaning. The correlation between the NIF index with outcomes of the weaning process was analyzed. Specificity (Sp), sensitivity (Se), positive predictive value (PPV), negative predictive value (NPV), receiver operating characteristic (ROC) curve, and area under the curve (AUC) were calculated.
The success rate of the entire weaning process was 67.2% (43/64). The median NIF values were –26.0 cm H2O (interquartile range [IQR], –28.0 to –25.0) in the successful weaning group and –24.0 cm H2O (IQR, –25.0 to –23.0) in the weaning failure group (P<0.001). According to ROC analysis, an NIF value ≤–25 cm H2O predicted weaning success (AUC, 0.836) with 91% Se, 62% Sp, 83% PPV, and 77% NPV.
An NIF cutoff threshold ≤–25 cm H2O can be used as predictor of weaning success in Vietnamese surgical intensive care patients.


Citations to this article as recorded by  
  • Pendelluft as a predictor of weaning in critically ill patients: An observational cohort study
    Danqiong Wang, Yaxin Ning, Linya He, Keqi Pan, Xiaohua Xiong, Shanshan Jing, Jianhua Hu, Jian Luo, Dehua Ye, Zubing Mei, Weiwen Zhang
    Frontiers in Physiology.2023;[Epub]     CrossRef
  • Morphological and Functional Alterations of Respiratory Muscle Performance and Spirometry Parameters in Patients with Congestive Heart Failure
    V. S. Shabaev, I. V. Orazmagomedova, V. A. Mazurok, A. V. Berezina, A. E. Bautin, L. G. Vasilyeva, D. A. Aleksandrova
    General Reanimatology.2023; 19(5): 39.     CrossRef
  • Diaphragmatic dysfunction in patients with chronic heart failure
    V.S. Shabaev, I.V. Orazmagomedova, V.A. Mazurok, A.V. Berezina, A.E. Bautin, L.G. Vasilyeva, D.A. Aleksandrova
    Anesteziologiya i reanimatologiya.2023; (5): 44.     CrossRef
  • Biosignal-Based Digital Biomarkers for Prediction of Ventilator Weaning Success
    Ji Eun Park, Tae Young Kim, Yun Jung Jung, Changho Han, Chan Min Park, Joo Hun Park, Kwang Joo Park, Dukyong Yoon, Wou Young Chung
    International Journal of Environmental Research and Public Health.2021; 18(17): 9229.     CrossRef

ACC : Acute and Critical Care