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Young Jae Oh 1 Article
Delayed Anaphylactic Shock to Intravenous Cefotetan in a Pregnant Woman: A Case Report
Ah Reum Cho, Hyeon Jeong Lee, Hye Kyung Park, Young Jae Oh
Korean J Crit Care Med. 2012;27(2):126-129.
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AbstractAbstract PDF
Anaphylactic reactions to agents administered intravenously usually occur within minutes. We present an unusual case of a delayed onset anaphylactic shock to intravenous cefotetan in a pregnant woman who underwent an epidural cesarean section. She sustained hypotension, tachycardia, bronchospasm, and rash 90 min after administering intravenous cefotetan. The possibilities of high epidural blocks or amnionic fluid embolisms were excluded by the height of sensory blocks or different presenting symptoms and signs, respectively. Allergic skin tests for exposed materials were performed 6 weeks after discharge and no immediate reactions occurred. However, delayed systemic allergic reactions, such as urticaria, rash, and edema on her face, neck, back, and abdomen, occurred 3 h after skin test to cefotetan.


Citations to this article as recorded by  
  • LC-MS/MS method for the quantitation of cefotetan in human plasma and its application to pharmacokinetic study
    Meiyun Shi, Lei Yin, Lanlan Cai, Can Wang, Xidong Liu, Sen Zhao, Yantong Sun, Paul J. Fawcett, Limei Zhao, Yan Yang, Jingkai Gu
    Chemical Research in Chinese Universities.2014; 30(6): 900.     CrossRef

ACC : Acute and Critical Care