1Department of Pulmonary, Allergy and Critical Care Medicine, Hallym University Kangnam Sacred Heart Hospital, Seoul, Korea
2Department of Pulmonary and Critical Care Medicine, Inha University College of Medicine, Incheon, Korea
3Department of Pulmonary and Critical Care Medicine, Yeungnam University Hospital, Daegu, Korea
4Department of Pulmonary and Critical Care Medicine, Inje University Sanggye Paik Hospital, Seoul, Korea
5Department of Internal Medicine, Myongji Hospital, Goyang, Korea
6Department of Pulmonary and Critical Care Medicine, Kyung Hee University Hospital at Gangdong, Seoul, Korea
7Department of Pulmonary and Critical Care Medicine, Chungnam National University Hospital, Daejeon, Korea
8Department of Internal Medicine, Pusan National University Hospital, Busan, Korea
9Department of Pulmonary, Critical Care and Sleep Medicine, St. Paul’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
10Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea
11Department of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea
12Department of Pulmonary, Allergy and Critical Care Medicine, Jeonbuk National University Hospital, Jeonju, Korea
13Department of Pulmonary, Allergy and Critical Care Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea
14Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
Copyright © 2020 The Korean Society of Critical Care Medicine
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
CONFLICT OF INTEREST Jae Hwa Cho has been the editor-in-chief of Acute and Critical Care since 2016 and an editorial board member since 2008.
AUTHOR CONTRIBUTIONS
Conceptualization: TK, JSK, EYC, YC, SP, JHC. Data curation: all authors. Formal analysis & Methodology: TK, JSK, SP, JHC. Visualization: TK, JHC. Writing–original draft: TK, SP, JHC. Writing–reviewing & editing: all authors.
Values are presented as mean±standard deviation or number (%).
SOFA: sequential organ failure assessment; NIV: noninvasive ventilation; RASS: Richmond Agitation-Sedation Scale; DM: diabetes mellitus; HTN: hypertension; CKD: chronic kidney disease; LC: liver cirrhosis; CVA: cerebrovascular accident; COPD: chronic obstructive pulmonary disease; ILD: interstitial lung disease; TB: tuberculosis.
Outcome | Control (n=129) | Sedation (n=26) | P-valuea |
---|---|---|---|
No. of complications | 45 (34.9) | 9 (34.6) | 0.979 |
Complication during NIV | |||
Skin erythema | 20 (15.5) | 6 (23.1) | 0.389 |
Abdominal distension | 6 (4.7) | 1 (3.8) | 1.000 |
Dry mouth | 5 (3.9) | 1 (3.8) | 1.000 |
Aspiration | 5 (3.9) | 0 | 0.590 |
Large leak | 16 (12.4) | 1 (3.8) | 0.309 |
Claustrophobia | 4 (3.1) | 0 | 1.000 |
Nasal congestion or sinus pain | 0 | 1 (3.8) | 0.168 |
Mucosal plugging | 1 (0.8) | 0 | 1.000 |
Medication | Sedation group (n=26) |
---|---|
Remifentanil | 15 (57.7) |
Dexmedetomidine | 8 (30.8) |
Fentanyl | 1 (3.8) |
Midazolam | 1 (3.8) |
Morphine | 1 (3.8) |