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Case Report
Neurology
Malignant Syndrome in Parkinson Disease Similar to Severe Infection
Dong Hun Lee, Jeong Mi Moon, Yong Soo Cho
Korean J Crit Care Med. 2017;32(4):359-362.   Published online December 29, 2016
DOI: https://doi.org/10.4266/kjccm.2016.00087
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AbstractAbstract PDF
A 70-year-old woman with Parkinson disease was admitted to the emergency department with altered consciousness, fever and convulsive movements without experiencing withdrawal from antiparkinsonian medication. Six hours after the emergency department visit, the patient had a hyperpyrexia (>40°C) and a systolic blood pressure of 40 mmHg. There was no evidence of bacterial infection based on extensive workups. The patient was discharged without aggravation of Parkinson disease symptoms after treatment that included administration of dantrolene sodium, enforcement of continuous renal replacement therapy and cooling blankets. Malignant syndrome should be suspected if high fever occurs in Parkinson disease patients without evidence of a definitive infection.

Citations

Citations to this article as recorded by  
  • Parkinsonism-Hyperpyrexia Syndrome and Dyskinesia-Hyperpyrexia Syndrome in Parkinson’s Disease: Two Cases and Literature Review
    Jian-Yong Wang, Jie-Fan Huang, Shi-Guo Zhu, Shi-Shi Huang, Rong-Pei Liu, Bei-Lei Hu, Jian-Hong Zhu, Xiong Zhang
    Journal of Parkinson's Disease.2022; 12(6): 1727.     CrossRef

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